ERCC1 Polyclonal Antibody, 20ul Multi-Layer Cell Culture System The protein encoded by PTGER3

The protein encoded by PTGER3 (prostaglandin E receptor 3) is a member of the G-protein coupled receptor family

where it participates in the export of mRNA from the nucleus

This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells

FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism

2 extracellular

ERCC1 Polyclonal Antibody, 20ul Multi-Layer Cell Culture System The protein encoded by PTGER3The product of ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in